Published Studies and Editorials

** Blue items denote or include studies that involved Dina Garbis Zaphiris of In Situ Foundation as dog trainer and handler.

General Studies on Cancer Detection and Electronic Noses

1) Evidence for Cancer Biomarkers in Exhaled Breath

Jan E. Szulejko, Michael McCulloch, Jennifer Jackson, Dwight L. McKee, Jim C. Walker, and Touradj Solouki

IEEE Sensors Journal, (2010) 10(1), 185-210

https://www.researchgate.net/profile/Michael_Mcculloch/publication/224092495_Evidence_for_Cancer_Biomarkers_in_Exhaled_Breath/links/540dcc5b0cf2f2b29a3a1915.pdf

2) Detection of Prostate Cancer by an Electronic Nose: A Proof of Principle Study

Antti Roine, Erik Veskima, Antti Tuokko, Pekka Kumpulainen, Juha Koskimaki, Tuomo A. Keinanen, Merja R. Hakkinen, Jouko Vepsalainen, Timo Paavonen, Jukka Lekkala, Terho Lehtimaki, Teuvo L. Tammela and Niku K. J. Oksala

The Journal of Urology (2014) 192, 230-235

http://www.jurology.com/article/S0022-5347(14)00303-6/abstract

3) Mimicking nature’s noses: From receptor deorphaning to olfactory biosensing

Richard Glatz, Kelly Bailey-Hill

Progress in Neurobiology (2011) 93, 270-296

http://www.sciencedirect.com/science/article/pii/S0301008210001954

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Studies on Cancer Detection Dogs

1) Analytical and unconventional methods of cancer detection using odor

Bogusław Buszewski, Joanna Rudnicka, Tomasz Ligor, Marta Walczak, Tadeusz Jezierski, Anton Amann

Trends in Analytical Chemistry (2012) 38, 1-12       

http://www.sciencedirect.com/science/article/pii/S0165993612001628

2) Canine scent detection of human cancers: A review of methods and accuracy

Emily Mosera , Michael McCulloch

Journal of Veterinary Behavior (2010) 5, 145-152

https://www.researchgate.net/profile/Michael_Mcculloch/publication/248578119_Canine_scent_detection_of_human_cancers_A_review_of_methods_and_accuracy/links/5405f6720cf2bba34c1df2d3.pdf

3) The Use of Canines in the Detection of Human Cancers

Robert T. Gordon, Carole Bech Schatz, Laurence J. Myers, Michaels Kosty, Constance Gonczy, Joan Kroener, Michael Tran, Pamela Kurtzhals, Susan Heath, James Koziol, Nan Arthur, Madeline Gabriel, Judy Hemping, Gordon Hemping, Sally Nesbitt, Lydia Tucker-Clark, Jennifer Zaayer

The Journal of Alternative and Complementary Medicine (2008), 14(1), 61–67

http://online.liebertpub.com/doi/abs/10.1089/acm.2006.6408

4) The possibility of inventing new technologies in the detection of cancer by applying elements of the canine olfactory apparatus

Alan Pomerantz, Ruben Blachman-Braun, Javier Andrés Galnares-Olalde, Roberto Berebichez-Fridman, Marino Capurso-García

Medical Hypotheses (2015) 85(2), 160-172

https://www.ncbi.nlm.nih.gov/pubmed/25936534

5) Colorectal cancer screening with odour material by canine scent detection

Hideto Sonoda, Shunji Kohnoe, Tetsuro Yamazato, Yuji Satoh, Gouki Morizono, Kentaro Shikata, Makoto Morita, Akihiro Watanabe, Masaru Morita, Yoshihiro Kakeji,1 Fumio Inoue, Yoshihiko Maehara

Gut (2011), 60, 814-819

http://gut.bmj.com/content/60/6/814

6) Diagnostic Accuracy of Canine Scent Detection in Early- and Late-Stage Lung and Breast Cancers

Michael McCulloch, Tadeusz Jezierski, Michael Broffman, Alan Hubbard, Kirk Turner, and Teresa Janecki

Integrative Cancer Therapies (2006) 5(1), 30-39

http://journals.sagepub.com/doi/pdf/10.1177/1534735405285096

 7) Evidence for canine olfactory detection of melanoma

Duane Pickel, Glenda P. Manucy, Dianne B. Walker, Sandra B. Hall, James C. Walker

Applied Animal Behaviour Science (2004) 89, 107-116

http://sniffoutcancer.org/images/Evidence-for-canine-olfactory-detection-of-melanoma_Pickel2004.pdf

 8) Human Ovarian Carcinomas Detected by Specific Odor

György Horvath, Gunvor af Klinteberg Järverud, Sven Järverud, István Horváth

Integrative Cancer Therapies (2008) 7(2), 76-80

https://www.researchgate.net/publication/5344831_Human_Ovarian_Carcinomas_Detected_by_Specific_Odor

 9) Cancer odor in the blood of ovarian cancer patients: a retrospective study of detection by dogs during treatment, 3 and 6 months afterward

György Horvath, Håkan Andersson and Szilárd Nemes

BMC Cancer (2013) 13:396

http://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-13-396

 10) Olfactory detection of human bladder cancer by dogs: proof of principle study

Carolyn M Willis, Susannah M Church, Claire M Guest, W Andrew Cook, Noel McCarthy, Anthea J Bransbury, Martin R T Church and John C T Church

BMJ (2004) 329:712

http://www.bmj.com/content/329/7468/712

 11) Olfactory System of Highly Trained Dogs Detects Prostate Cancer in Urine Samples

Gianluigi Taverna, Lorenzo Tidu, Fabio Grizzi, Valter Torri, Alberto Mandressi, Paolo Sardella, Giuseppe La Torre, Giampiero Cocciolone, Mauro Seveso, Guido Giusti, Rodolfo Hurle, Armando Santoro and Pierpaolo Graziotti

The Journal of Urology (2015) 193(4), 1382-1387

STUDY: https://www.ncbi.nlm.nih.gov/pubmed/25264338

ARTICLE: http://www.harvardprostateknowledge.org/trained-dogs-can-sniff-prostate-cancer

12) Olfactory Detection of Prostate Cancer by Dogs Sniffing Urine: A Step Forward in Early Diagnosis

Jean-Nicolas Cornu, Ge ́raldine Cancel-Tassin, Vale ́rie Ondet, Caroline Girardet, Olivier Cussenot

European Urology (2011) 59(2), 197-201

http://www.europeanurology.com/article/S0302-2838(10)00944-9/pdf/olfactory-detection-of-prostate-cancer-by-dogs-sniffing-urine-a-step-forward-in-early-diagnosis

13) Key considerations for the experimental training and evaluation of cancer odour detection dogs: lessons learnt from a double-blind, controlled trial of prostate cancer detection

Kevin R Elliker, Barbara A Sommerville, Donald M Broom, David E Neal, Sarah Armstrong and Hywel C Williams

BMC Urology (2014) 14:22

http://bmcurol.biomedcentral.com/articles/10.1186/1471-2490-14-22

14) Canine scent detection in the diagnosis of lung cancer: Revisiting a puzzling phenomenon

Rainer Ehmann, Enole Boedeker, Uwe Friedrich, Jutta Sagert, Jürgen Dippon, Godehard Friedel, Thorsten Walles

European Respiratory Journal (2012) 39(3), 669-676

https://www.researchgate.net/profile/Juergen_Dippon/publication/51581463_Canine_scent_detection_in_the_diagnosis_of_lung_cancer_Revisiting_a_puzzling_phenomenon/links/56c1b3a708ae44da37fe4628.pdf

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Other Studies on Medical Detection Dogs

1) Detection of Bacteriuria by Canine Olfaction

Maureen Maurer, Michael McCulloch, Angel M. Willey, Wendi Hirsch, and Danielle Dewey

Open Forum Infectious Diseases, 2012

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866566/

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Editorials, Letters to the Editor on Cancer Detection Dogs

1) Detection of Prostate Cancer in Urine by Dogs

Robert R. Bahnson

The Journal of Urology, (2015) 193, 1083

http://www.jurology.com/article/S0022-5347(15)00086-5/fulltext

2) Dogs Sniffing Urine: A Future Diagnostic Tool or a Way to Identify New Prostate Cancer Markers?

Anders S. Bjartell

European Urology (2011) 59, 202-203

http://www.europeanurology.com/article/S0302-2838(10)00998-X/fulltext/dogs-sniffing-urine-a-future-diagnostic-tool-or-a-way-to-identify-new-prostate-cancer-markers

3) Olfactory Detection of Prostate Cancer by Dogs Sniffing Urine – Letter to the Editor

Giuseppi Lippi

European Urology (2011) 60, e29

http://www.europeanurology.com/article/S0302-2838(11)00654-3/fulltext/re-jean-nicolas-cornu-g-x000e9-raldine-cancel-tassin-val-x000e9-rie-ondet-et-al-olfactory-detection-of-prostate-cancer-by-dogs-sniffing-urine-a-step-forward-in-early-diagnosis-eur-urol-2011-59-197-201